Article
Prolactin maintains the neonatal phenotype of enterocytes during lactation in newborn mice.
American journal of physiology. Cell physiology - 1 Jul 2025
Dena-Beltrán José Luis, Ocampo-Ruiz Ana Luisa, Vázquez-Carrillo Dina I, de Los Ríos Ericka A, Ruiz-Herrera Xarubet, Valle-Pacheco Magali, Robles-Torres Sairi I, Martínez de la Escalera Gonzalo, Clapp Carmen, Macotela Yazmín
Abstract excerpt
After birth, the intestine experiences a gradual maturation process that transforms the gut epithelium to adapt to the changing feeding conditions, from maternal milk to solid food. Milk components regulate this transition from neonatal- to adult-type enterocytes. Prolactin (PRL), a hormone present in milk at high concentrations, regulates the metabolism of the nursing pups. However, the target tissues that...
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