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[An intron-free methyl jasmonate inducible geranylgeranyl diphosphate synthase gene from Taxus media and its functional identification in yeast].

Molekuliarnaia biologiia - 1 Jan 2000

Liao Zhihua, Gong Yifu, Kai Guoyin, Zuo Kaijing, Chen Min, Tan Qiumin, Wei Yamin, Guo Liang, Tan Feng, Sun Xiaofen, Tang Kexuan

Abstract excerpt

Geranylgeranyl diphosphate synthase (GGPPS, EC: 2.5.1.29) catalyzes the biosynthesis of geranylgeranyl diphosphate (GGPP), which is a key precursor for diterpenes including Taxol, one of the most potent antitumor drugs. In order to investigate the role of GGPP synthase in taxol biosynthesis, we cloned, characterized and functionally expressed the GGPP synthase gene from Taxus media. A 3743-bp genomic sequence of...

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PMID: 15773543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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