Article
Blackpatch, a neural degeneration mutation that interacts with the Notch locus in Drosophila.
Developmental biology - 1 May 1992
Duus K M, Welshons W J, Girton J R
Abstract excerpt
We have identified a gene in Drosophila melanogaster that is involved in the development of the adult eye and optic lobe of the brain and that interacts with facet alleles at the Notch locus. We have named this locus Blackpatch (Bpt). Mutant alleles of Bpt produce a variety of abnormal phenotypes in the presence of facet alleles. These phenotypes include neural degeneration in the eye and in the optic lobe of the...
Topics
- Alleles
- Animals
- Cell Communication
- Drosophila melanogaster
- Female
- Genes, Lethal
- Male
- Morphogenesis
- Mutagenesis
- Mutation
- Optic Lobe, Nonmammalian
- Phenotype
