Isolation, characterization and functional activity of human marrow stromal progenitors in hemopoiesis.

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Article

Isolation, characterization and functional activity of human marrow stromal progenitors in hemopoiesis.

Progress in clinical and biological research - 1 Jan 1994

Simmons P J, Gronthos S, Zannettino A, Ohta S, Graves S

Abstract excerpt

In conclusion, monoclonal antibody STRO-1 has proven to be an extremely valuable reagent for the identification, isolation and functional characterization of human bone marrow stromal cell precursors. We were able to isolate CFU-F free of contaminating hemopoietic progenitors and are beginning to construct a detailed picture of their cell surface phenotype and have developed assays to examine the conditions...

Topics

Adult
Animals
Antibodies, Monoclonal
Antigens, Surface
Bone Marrow
Bone Marrow Cells
Cell Division
Cell Membrane
Cell Separation
Colony-Forming Units Assay
Hematopoiesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hematopoietic Stem Cells

Humans

In Vitro Techniques

Mice

Models, Biological

Phenotype

Source

Open in PubMed

Identifiers

PMID: 7700911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7700911-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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