Article
Whole-body insulin sensitivity index is a highly specific predictive marker for virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients with genotype 1b and high viral load.
Digestive diseases and sciences - 1 Jan 2010
Mizuta Toshihiko, Kawaguchi Yasunori, Eguchi Yuichiro, Takahashi Hirokazu, Ario Keisuke, Akiyama Takumi, Oza Noriko, Otsuka Taiga, Kuwashiro Takuya, Yoshimura Toru, Hisatomi Akitaka, Ozaki Iwata
Abstract excerpt
Insulin resistance is a candidate predictive factor for virological response to peginterferon plus ribavirin (PEG/RBV) therapy in chronic hepatitis C patients. We examined whether indices of insulin resistance could serve as a predictor of sustained virological response (SVR). Fifty-one patients with genotype 1b and high viral load who received PEG/RBV therapy for 48 weeks were included. Homeostasis model...
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