Article
XRCC1 polymorphisms are associated with cervical cancer risk and response to chemotherapy: a systematic review and meta-analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Shuai Han-Lin, Luo Xin, Yan Rui-Ling, Li Jian, Chen Dan-Liang
Abstract excerpt
BACKGROUND: Functional single nucleotide polymorphisms of x-ray repair cross-complementing protein 1 (XRCC1) have been suspected to contribute to uterine cervical cancer risk for a long time; however, most previous case-control studies were small sized and biased. Additionally, recent studies suggested that XRCC1 polymorphisms could be a biomarker of response to platinum-based chemotherapy. METHODS: A...
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