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Article

Lipopolysaccharides from Helicobacter pylori can act as antagonists for Toll-like receptor 4

25 Jan 2005

Abstract excerpt

Infection with Helicobacter pylori, a Gram-negative bacterium, is strongly associated with gastric ulcers and adenocarcinoma. The mechanisms by which the innate immune system recognizes H. pylori lipopolysaccharide (LPS) remain unclear. Contradictory reports exist that suggest that Toll-like receptors are involved. In this study we evaluated the interactions of Toll-like receptors with LPS from different strains...

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PMID: 15760452
DOI: 10.1111/j.1462-5822.2005.00482.x

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