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Article

Parameterization of a nonlinear genotype to phenotype map using molecular networks.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2005

Peccoud Jean, Velden Kent Vander

Abstract excerpt

Mathematical models of networks of molecular interactions controlling the expression of traits could theoretically be used as genotype to phenotype (GP) maps. Such maps are nonlinear functions of the environment and the genotype. It is possible to use nonlinear least square minimization methods to fit a model to a set of phenotypic data but the convergence of these methods is not automatic and may lead to a...

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PMID: 15759634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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