Article
Threshold gradient descent method for censored data regression with applications in pharmacogenomics.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2005
Gui J, Li H
Abstract excerpt
An important area of research in pharmacogenomics is to relate high-dimensional genetic or genomic data to various clinical phenotypes of patients. Due to large variability in time to certain clinical event among patients, studying possibly censored survival phenotypes can be more informative than treating the phenotypes as categorical variables. In this paper, we develop a threshold gradient descent (TGD) method...
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