Article
Integrative analysis of cancer prognosis data with multiple subtypes using regularized gradient descent.
Genetic epidemiology - 1 Dec 2012
Ma Shuangge, Zhang Yawei, Huang Jian, Huang Yuan, Lan Qing, Rothman Nathaniel, Zheng Tongzhang
Abstract excerpt
In cancer research, high-throughput profiling studies have been extensively conducted, searching for genes/single nucleotide polymorphisms (SNPs) associated with prognosis. Despite seemingly significant differences, different subtypes of the same cancer (or different types of cancers) may share common susceptibility genes. In this study, we analyze prognosis data on multiple subtypes of the same cancer but note...
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