Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Schistosomal hepatic fibrosis and the interferon gamma receptor: a linkage analysis using single-nucleotide polymorphic markers.

European journal of human genetics : EJHG - 1 May 2005

Blanton Ronald E, Salam Ekram Abdel, Ehsan Amgad, King Charles H, Goddard Katrina Ab

Abstract excerpt

A minority of individuals infected with the parasite Schistosoma mansoni develops hepatic fibrosis. HLA studies in Egypt and a candidate gene search in a Sudanese population indicate that the host's genetics contribute to disease susceptibility. In an Egyptian community, 32.7% of individuals 11 years and older had significant fibrosis by WHO ultrasound criteria. Linkage to 10 candidate genes was tested using 89...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Egypt
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon gamma Receptor

Share to Interleukin-13

Share to Liver Cirrhosis

Share to Receptors, Interferon

Share to Schistosomiasis mansoni

Share to Ultrasonography

Source

Identifiers

PMID: 15756299
DOI: 10.1038/sj.ejhg.5201388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Schistosomal hepatic fibrosis and the interferon gamma receptor: a linkage analysis using single-nucleotide polymorphic markers.PMID 15756299Read ↗

Severe hepatic fibrosis in Schistosoma mansoni infection is controlled by a major locus that is closely linked to the interferon-gamma receptor gene.Semantic proximity Read ↗

[Genetic predisposition to bilharziasis in humans: research methods and application to the study of Schistosoma mansoni infection].Semantic proximity Read ↗

IFN-gamma polymorphisms (IFN-gamma +2109 and IFN-gamma +3810) are associated with severe hepatic fibrosis in human hepatic schistosomiasis (Schistosoma mansoni).Semantic proximity Read ↗

Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection.Semantic proximity Read ↗

Genetic epidemiology of human schistosomiasis in Brazil.Semantic proximity Read ↗

Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.Semantic proximity Read ↗

The Genetics of Human Schistosomiasis Infection Intensity and Liver Disease: A Review.Semantic proximity Read ↗

Description of three new polymorphisms in the intronic and 3'UTR regions of the human interferon gamma gene.Semantic proximity Read ↗

Genetic control of visceral leishmaniasis in a Sudanese population: candidate gene testing indicates a linkage to the NRAMP1 region.Semantic proximity Read ↗

Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33.Semantic proximity Read ↗

Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.Semantic proximity Read ↗

Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.