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Article

Susceptibility to leprosy may be conditioned by an interaction between the NRAMP1 promoter polymorphisms and the lepromin response.

International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association - 1 Dec 2004

Ferreira Frederico Rogério, Goulart Luiz Ricardo, Silva Heyder Diniz, Goulart Isabela Maria Bernardes

Abstract excerpt

Controversial results have been achieved by attempting to associate the NRAMP1 gene with Mycobacterium leprae susceptibility as well as with the Mitsuda reaction, which represents a specific immune response to M. leprae. This study evaluated this association as well as the interaction of the polymorphism (GT)(n) in the promoter region of the NRAMP1 gene with a specific immune response to M. leprae measured by the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15755200
DOI: 10.1489/1544-581X(2004)72<457:STLMBC>2.0.CO;2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Susceptibility to leprosy may be conditioned by an interaction between the NRAMP1 promoter polymorphisms and the lepromin response.PMID 15755200Read ↗

Association of NRAMP1 polymorphism with leprosy type but not susceptibility to leprosy per se in west Africans.Semantic proximity Read ↗

Comparative analysis of natural resistance-associated macrophage protein 1 gene expression and anti-PGL-1 antibodies in multibacillary leprosy and household contacts.Semantic proximity Read ↗

Susceptibility to leprosy is linked to the human NRAMP1 gene.Semantic proximity Read ↗

[NRAMP1 gene polymorphisms in individuals with leprosy reactions attended at two reference centers in Recife, northeastern Brazil].Semantic proximity Read ↗

Association of the solute carrier family 11 member 1 gene polymorphisms with susceptibility to leprosy in a Brazilian sample.Semantic proximity Read ↗

[The genetic susceptibility to leprosy in humans].Semantic proximity Read ↗

Granulomatous reaction to intradermal injection of lepromin (Mitsuda reaction) is linked to the human NRAMP1 gene in Vietnamese leprosy sibships.Semantic proximity Read ↗

Association of NRAMP1 promoter gene polymorphism with the susceptibility and radiological severity of rheumatoid arthritis.Semantic proximity Read ↗

Polymorphisms of the NRAMP1 gene: distribution and susceptibility to the development of pulmonary tuberculosis in the Greek population.Semantic proximity Read ↗

Interaction of TaqI polymorphism at exon 9 of the vitamin D receptor gene with the negative lepromin response may favor the occurrence of leprosy.Semantic proximity Read ↗

No evidence of linkage between Mitsuda reaction and the NRAMP1 locus.Semantic proximity Read ↗

NRAMP1 genetic polymorphisms as a risk factor of tuberculous pleurisy.Semantic proximity Read ↗

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