Article
NRAMP1 genetic polymorphisms as a risk factor of tuberculous pleurisy.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Apr 2003
Kim J H, Lee S Y, Lee S H, Sin C, Shim J J, In K H, Yoo S H, Kang K H
Abstract excerpt
SETTING: Nrampl encoded by the NRAMP1 gene influences the phagolysosomal function of alveolar macrophage against Mycobacterium tuberculosis. Genetic polymorphisms of NRAMP1 affect innate host resistance through the defective production and function of Nrampl. OBJECTIVE: To investigate this relationship, the NRAMP1 polymorphisms in patients with tuberculous pleurisy were determined. DESIGN: Pleural biopsy proven...
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