Article
IBD5 polymorphisms in inflammatory bowel disease: association with response to infliximab.
World journal of gastroenterology - 28 Feb 2005
Urcelay Elena, Mendoza Juan-Luis, Martinez Alfonso, Fernandez Laura, Taxonera Carlos, Diaz-Rubio Manuel, de la Concha Emilio-G
Abstract excerpt
AIM: Inflammatory bowel diseases (IBD) are multifactorial pathologies of unknown etiology. One susceptibility locus, IBD5, has been mapped to chromosome 5q31. We analyzed our Spanish cohorts of Crohn's disease (CD) and ulcerative colitis (UC) patients to determine whether this locus is associated with IBD, and to ascertain the main clinical phenotype influenced by this risk factor. The kind of interaction, either...
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