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Article

Polymorphisms and mutations of the folate receptor-alpha gene and risk of gastric cancer in a Chinese population.

International journal of molecular medicine - 1 Apr 2005

Zhang Gui, Zhang Qing-Ying, Miao Xiao-Ping, Lin Dong-Xin, Lu You-Yong

Abstract excerpt

Folate deficiency is associated with increased risk of many human diseases including several cancers. Folate receptor-alpha (FR-alpha) plays an important role in mediating influx of folates into cells and its expression can be induced by some environmental risk factors. Our previous study showed that decreased expression of FR-alpha occurs in human gastric cancer cell lines. In order to reveal the molecular...

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PMID: 15754024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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