Article
Does memory improve with age? CD85j (ILT‐2/LIR‐1) expression on CD8<sup>+</sup> T cells correlates with ‘memory inflation’ in human cytomegalovirus infection
4 Mar 2005
Abstract excerpt
CMV-specific memory CD8(+) T cells accumulate over time to reach high frequencies amongst peripheral blood lymphocytes - a phenomenon termed 'memory inflation'. Using tetramer staining on samples from a large number of subjects and multivariate regression analysis, we were able to relate this to the phenotype of CD8(+) T cells. We made the following observations: (i) CD85j (ILT-2/LIR-1) was highly expressed...
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