Article
Heterogeneity of the genetic risk in age-related macular disease: a population-based familial risk study.
Ophthalmology - 1 Mar 2005
Assink Jacqueline J M, Klaver Caroline C W, Houwing-Duistermaat Jeanine J, Wolfs Roger C W, van Duijn Cornelia M, Hofman Albert, de Jong Paulus T V M
Abstract excerpt
OBJECTIVE: To assess the extent of heterogeneity of the genetic risk of age-related macular disease (AMD) among families. DESIGN: Case-controlled population-based familial aggregation study. PARTICIPANTS: Participants comprised 190 first-degree relatives of 65 case probands and 347 relatives of 100 control probands. All probands had been identified from the baseline phase of the Rotterdam Study in The...
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