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Article

Biological Implications of <i>Mycobacterium leprae</i> Gene Expression during Infection

1 Jan 2004

Abstract excerpt

The genome of Mycobacterium leprae, the etiologic agent of leprosy, has been sequenced and annotated revealing a genome in apparent disarray and in stark contrast to the genome of the related human pathogen, M. tuberculosis. With less than 50% coding capacity of a 3.3-Mb genome and 1,116 pseudogenes, the remaining genes help define the minimal gene set necessary for in vivo survival of this mycobacterial pathogen...

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PMID: 15741741
DOI: 10.1159/000082081

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