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Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers

28 Feb 2005

Abstract excerpt

Human cytomegalovirus (HCMV) persists as a subclinical, lifelong infection in the normal human host, but reactivation from latency in immunocompromised subjects results in serious disease. Latency and reactivation are defining characteristics of the herpesviruses and are key to understanding their biology; however, the precise cellular sites in which HCMV is carried and the mechanisms regulating its latency and...

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PMID: 15738399
DOI: 10.1073/pnas.0408994102

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