Article
A Gluconobacter oxydans mutant converting glucose almost quantitatively to 5-keto-D-gluconic acid.
Applied microbiology and biotechnology - 1 Mar 2005
Elfari Mustafa, Ha Seung-Wook, Bremus Christoph, Merfort Marcel, Khodaverdi Viola, Herrmann Ute, Sahm Hermann, Görisch Helmut
Abstract excerpt
Gluconobacter oxydans converts glucose to gluconic acid and subsequently to 2-keto-D-gluconic acid (2-KGA) and 5-keto-D-gluconic acid (5-KGA) by membrane-bound periplasmic pyrroloquinoline quinone-dependent and flavin-dependent dehydrogenases. The product pattern obtained with several strains differed significantly. To increase the production of 5-KGA, which can be converted to industrially important...
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