Sex and death: what is the connection?

Abstract excerpt

A cost of reproduction, where lifespan and fecundity are negatively correlated, is of widespread occurrence. Mutations in insulin/IGF signaling (IIS) pathways and dietary restriction (DR) can extend lifespan in model organisms but do not always reduce fecundity, suggesting that the link between lifespan and fecundity is not inevitable. Understanding the molecular basis of the cost of reproduction will be informed...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Caloric Restriction
• Share to Insulin
• Share to Insulin-Like Growth Factor I