Article
Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C.
Hepatology (Baltimore, Md.) - 1 Apr 2005
Reiser Markus, Hinrichsen Holger, Benhamou Yves, Reesink Henk W, Wedemeyer Heiner, Avendano Cristina, Riba Neus, Yong Chan-Loi, Nehmiz Gerhard, Steinmann Gerhard G
Abstract excerpt
BILN-2061, a specific and potent peptidomimetic inhibitor of the HCV NS3 protease, has recently been shown to markedly lower serum hepatitis C virus (HCV)-RNA levels in patients chronically infected with HCV genotype 1 in three 2-day proof of principle studies. The aim of the current study was to assess the antiviral efficacy of BILN-2061 in patients with genotypes 2 and 3 HCV infection. The antiviral efficacy,...
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