Article
SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders.
Gastroenterology - 1 Apr 2007
Sarrazin Christoph, Rouzier Regine, Wagner Frank, Forestier Nicole, Larrey Dominique, Gupta Samir K, Hussain Musaddeq, Shah Amrik, Cutler David, Zhang Jenny, Zeuzem Stefan
Abstract excerpt
BACKGROUND & AIMS: SCH 503034 is a novel and potent oral hepatitis C virus (HCV) protease inhibitor. In this phase Ib study, we assessed safety parameters and virologic response of combination of SCH 503034 plus pegylated (PEG) interferon (IFN) alpha-2b in patients with HCV genotype 1 infections who were previously nonresponders to PEG-IFN-alpha-2b +/- ribavirin therapy. METHODS: This was a multicenter,...
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