Article
No association between the ERBB3 gene and schizophrenia in a Japanese population.
Neuroscience research - 1 Apr 2007
Watanabe Yuichiro, Fukui Naoki, Nunokawa Ayako, Muratake Tatsuyuki, Kaneko Naoshi, Kitamura Hideaki, Someya Toshiyuki
Abstract excerpt
There is cumulative evidence that neuregulin 1 (NRG1) is a susceptibility gene for schizophrenia. Postmortem studies on brains from schizophrenia patients have revealed changes in the mRNA expression levels of v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (ERBB3), one of the NRG1 receptor genes. These observations suggest that NRG1-ERBB signaling is involved in the pathogenesis of schizophrenia. To...
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