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Article

The role of the epidermal growth factor in the pathogenesis of schizophrenia. Clinical and diagnostic value.

Growth factors (Chur, Switzerland) - 1 May 2026

Piskareva Daria, Zorkina Yana, Andryushenko Alisa, Kostyuk Georgy

Abstract excerpt

Research increasingly implicates neuroimmune inflammation in schizophrenia, with the epidermal growth factor (EGF) family as a potential link. This review critically evaluates EGF family members as diagnostic, risk, and treatment response markers.The most consistent finding is decreased serum EGF in chronic schizophrenia, confirmed in postmortem brain and independent of antipsychotics. First-episode data are...

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Source

Identifiers

PMID: 42390996
DOI: 10.1080/08977194.2026.2695623

Genes

EGF
NRG1
NRG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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