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Article

Ligand activated relaxin receptor increases the transcription of IGFBP-1 and prolactin in human decidual and endometrial stromal cells.

Molecular human reproduction - 1 Apr 2005

Tang Meiyi, Mazella James, Zhu Hui Hui, Tseng Linda

Abstract excerpt

The aim of this study was to investigate relaxin (RLX) receptor-mediated gene activation in human endometrium. We determined the promoter activities of insulin-like growth factor binding protein-1 (IGFBP-1) and prolactin (PRL) and identified sequence(s) that mediate RLX activated transcription in human decidual cells and endometrial stromal cells. In human decidual cells, the promoter activity of IGFBP-1 was...

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Source

Identifiers

PMID: 15722441
DOI: 10.1093/molehr/gah149

Genes

PRL
EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Ligand activated relaxin receptor increases the transcription of IGFBP-1 and prolactin in human decidual and endometrial stromal cells.PMID 15722441Read ↗

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Progesterone Receptor (hPR) Upregulates the Fibronectin Promoter Activity in Human Decidual FibroblastsSemantic proximity Read ↗

Induction of IGFBP-1 Expression by cAMP Is Associated with Histone Acetylation Status of the Promoter Region in Human Endometrial Stromal CellsSemantic proximity Read ↗

Progesterone receptor (PR) inhibits expression of insulin-like growth factor-binding protein-1 (IGFBP-1) in human endometrial cell line HEC-1B: characterization of the inhibitory effect of PR on the distal promoter region of the IGFBP-1 gene.Semantic proximity Read ↗

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Distal Sp3 binding sites in the hIGBP-1 gene promoter suppress transcriptional repression in decidualized human endometrial stromal cells: identification of a novel Sp3 form in decidual cells.Semantic proximity Read ↗

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