Article
Activation of the human IGFBP-1 gene promoter by progestin and relaxin in primary culture of human endometrial stromal cells.
Molecular and cellular endocrinology - 1 Aug 1994
Gao J G, Mazella J, Tseng L
Abstract excerpt
We have studied the activity for the insulin-like growth factor binding protein-1 (IGFBP-1) gene promoter in human endometrial stromal cells by transient transfection. The promoter activity derived from p3.6CAT or p3.6Luc (3400 bp IGFBP-1 promoter 5' to the reporter gene chloramphenicol acetyltransferase or luciferase) was minimal in unstimulated cells. A time study over 13 days of culture showed that the...
Topics
- Adult
- Base Sequence
- Carrier Proteins
- Cells, Cultured
- Endometrium
- Female
- Gene Deletion
- Gene Expression Regulation
- Humans
- Insulin-Like Growth Factor Binding Protein 1
- Medroxyprogesterone Acetate
