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Article

Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion.

Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 2005

Schimenti John C, Reynolds Jennifer L, Planchart Antonio

Abstract excerpt

Transmission ratio distortion (TRD) and sterility are male-specific quantitative trait phenomena associated with the mouse t haplotype. TRD occurs in t haplotype-heterozygous males and is caused by the deleterious action of distorter products on sperm bearing a wild-type responder locus. It has been proposed that t-mediated male sterility is a severe manifestation of TRD caused by homozygosity for distorter loci;...

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Identifiers

PMID: 15722415
DOI: 10.1073/pnas.0407970102
PMCID: PMC552908

Genes

TRD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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