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Article

Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages.

The Journal of biological chemistry - 29 Apr 2005

Trebino Catherine E, Eskra James D, Wachtmann Timothy S, Perez Jose R, Carty Thomas J, Audoly Laurent P

Abstract excerpt

Microsomal prostaglandin E synthase (mPGES)-1 is one of several prostaglandin E synthases involved in prostaglandin H2 (PGH2) metabolism. In the present report, we characterize the contribution of mPGES-1 to cellular PGH2 metabolism in murine macrophages by studying the synthesis of eicosanoids a...

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Source

Identifiers

PMID: 15722356
DOI: 10.1074/jbc.M412075200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15722356-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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