Article
Glucose transporters in diabetic nephropathy.
Pediatric nephrology (Berlin, Germany) - 1 Apr 2005
Brosius Frank C, Heilig Charles W
Abstract excerpt
Changes in glucose transporter expression in glomerular cells occur early in diabetes. These changes, especially the GLUT1 increase in mesangial cells, appear to play a pathogenic role in the development of ECM expansion and perhaps other features of diabetic nephropathy. In addition, it appears that at least some diabetic patients may be predisposed to nephropathy because of polymorphisms in their GLUT1 genes....
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