Article
Role for GLUT1 in diabetic glomerulosclerosis.
Expert reviews in molecular medicine - 6 Feb 2006
Heilig Charles W, Brosius Frank C, Cunningham Carol
Abstract excerpt
Numerous studies have investigated specific pathways that link diabetes and high extracellular glucose exposure to glomerulosclerosis and mesangial cell extracellular matrix production. However, only in the past ten years has a role for glucose transporters in this process been addressed. Many different glucose transporters are expressed in glomeruli; of these, the GLUT1 facilitative glucose transporter is...
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