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Article

Caldesmon over-expression in type 1 diabetic nephropathy.

Journal of diabetes and its complications - 1 Jan 2000

Millioni Renato, Iori Elisabetta, Lenzini Livia, Puricelli Lucia, Caroccia Brasilina, Arrigoni Giorgio, Rossi Gian Paolo, Tessari Paolo

Abstract excerpt

Substantial evidence supports a genetic susceptibility to develop nephropathy in type 1 diabetes and a key pathogenic role of actin cytoskeleton dysfunction in this complication. We previously reported that many cytoskeletal proteins were either up- or down-regulated in fibroblast cells from type 1 diabetic (T1DM) patients with nephropathy. The gene of one of these proteins, caldesmon, lies in a chromosomal...

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Identifiers

PMID: 20801058
DOI: 10.1016/j.jdiacomp.2010.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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