Article
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.
The Journal of allergy and clinical immunology - 1 Nov 2011
Ramasamy Adaikalavan, Curjuric Ivan, Coin Lachlan J, Kumar Ashish, McArdle Wendy L, Imboden Medea, Leynaert Benedicte, Kogevinas Manolis, Schmid-Grendelmeier Peter, Pekkanen Juha, Wjst Matthias, Bircher Andreas J, Sovio Ulla, Rochat Thierry, Hartikainen Anna-Liisa, Balding David J, Jarvelin Marjo-Riitta, Probst-Hensch Nicole, Strachan David P, Jarvis Deborah L
Abstract excerpt
BACKGROUND: Hay fever or seasonal allergic rhinitis (AR) is a chronic disorder associated with IgE sensitization to grass. The underlying genetic variants have not been studied comprehensively. There is overwhelming evidence that those who have older siblings have less AR, although the mechanism...
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