Article
Detection of rampant nucleotide reversion at the origin of DNA replication of porcine circovirus type 1.
Virology - 1 Mar 2005
Cheung Andrew K
Abstract excerpt
Mutational analysis was conducted to investigate the involvement of the "loop-sequence" (which is flanked by a pair of 11-nucleotide inverted repeats) at the origin of DNA replication of porcine circovirus type 1 with respect to viral protein synthesis, DNA self-replication and progeny virus production. The results demonstrated that an octanucleotide (A1G2T3A4T5T6A7C8) embedded in the loop is essential for viral...
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