Article
Association of Helicobacter pylori-related distal gastric cancer with the HLA class II gene DQB10602 and cagA strains in a southern European population.
Helicobacter - 1 Feb 2005
Quintero Enrique, Pizarro M Angeles, Rodrigo Luis, Piqué Josep M, Lanas Angel, Ponce Julio, Miño Gonzalo, Gisbert Javier, Jurado Aurora, Herrero M José, Jiménez Alejandro, Torrado Julio, Ponte Ana, Díaz-de-Rojas Francisco, Salido Eduardo
Abstract excerpt
BACKGROUND: Distinct human leukocyte antigen (HLA)-DQ genes have been associated with an increased or reduced risk for gastric cancer, but its association with Helicobacter pylori status is controversial. In the present study we evaluated the influence of host HLA DQA1 and DQB1 loci, H. pylori genotype, and socio-economic factors on predicting H. pylori-associated distal gastric cancer in a southern European...
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