Article
Polymorphisms in HLA-DQ genes, together with age, sex, and Helicobacter pylori infection, as potential biomarkers for the early diagnosis of gastric cancer.
Helicobacter - 1 Feb 2017
Pérez-Rodríguez Martha, Partida-Rodríguez Oswaldo, Camorlinga-Ponce Margarita, Flores-Luna Lourdes, Lazcano Eduardo, Gómez Alejandro, Herrera-Goepfert Roberto, Medrano-Guzmán Rafael, Torres Javier
Abstract excerpt
BACKGROUND: Polymorphisms in inflammation-related genes are factors associated with the development of gastroduodenal diseases in Helicobacter pylori-infected individuals. MATERIALS AND METHODS: We aimed to analyze polymorphisms in HLA-DQ, together with other host and H. pylori variables as risk factors for precancerous and cancerous gastric lesions. 1052 individuals were studied, including nonatrophic gastritis...
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