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Mesenchymal progenitor cells localize within hematopoietic sites throughout ontogeny

3 Feb 2005

Abstract excerpt

Mesenchymal stem cells (MSCs) have great clinical potential for the replacement and regeneration of diseased or damaged tissue. They are especially important in the production of the hematopoietic microenvironment, which regulates the maintenance and differentiation of hematopoietic stem cells (HSCs). In the adult, MSCs and their differentiating progeny are found predominantly in the bone marrow (BM). However, it...

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PMID: 15689383
DOI: 10.1242/dev.01615

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