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Article

Immunobiology of Her-2/Neu Transgenic Mice

24 Nov 2004

Abstract excerpt

Development of the mammary gland is controlled by hormones and many other growth factors. Hyperplasia and neoplasia are thus a likely consequence of alterations in their number and type, or the number and function of their receptors. p185neu, a member of the epidermal growth factor family, is coded by the ErbB-2 oncogene. It is expressed in the normal human breast, but overexpressed and associated with a poor...

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PMID: 15687705
DOI: 10.3233/bd-2004-20105

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