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Article

Stability of fluoroquinolone resistance in Streptococcus pneumoniae clinical isolates and laboratory-derived mutants.

Antimicrobial agents and chemotherapy - 1 Feb 2005

Smith-Adam Heather J, Nichol Kimberly A, Hoban Daryl J, Zhanel George G

Abstract excerpt

The stability of fluoroquinolone resistance in Streptococcus pneumoniae was evaluated in laboratory-derived mutants and clinical isolates. Isolates with various genotypes and phenotypes were subcultured for 20 days on antibiotic-free media and were monitored by E-tests to identify any alterations in resistance. Fluoroquinolone resistance mechanisms, whether efflux or chromosomally mediated, remained stable in...

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Identifiers

PMID: 15673786
DOI: 10.1128/AAC.49.2.846-848.2005
PMCID: PMC547370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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