Article
Clinical isolates of Streptococcus pneumoniae with different susceptibilities to ceftriaxone and cefotaxime.
Antimicrobial agents and chemotherapy - 1 Oct 2003
Karlowsky James A, Jones Mark E, Draghi Deborah C, Sahm Daniel F
Abstract excerpt
Ceftriaxone and cefotaxime are extended-spectrum cephalosporins previously demonstrated to possess very similar in vitro activities against Streptococcus pneumoniae. Anecdotal reports of isolates with divergent in vitro susceptibilities to ceftriaxone and cefotaxime have been published. To determine the prevalence of pneumococcal isolates with divergent ceftriaxone and cefotaxime susceptibilities, we tested 1,000...
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