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In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques

30 Oct 2017

Abstract excerpt

Nonhuman primates are the only mammals to possess a true macula similar to humans, and spontaneously develop drusenoid lesions which are hallmarks of age-related macular degeneration (AMD). Prior studies demonstrated similarities between human and nonhuman primate drusen based on clinical appearance and histopathology. Here, we employed fundus photography, spectral domain optical coherence tomography (SD-OCT),...

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PMID: 29101353
DOI: 10.1038/s41598-017-14715-z

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