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Article

Identification and Characterization of the Protein-associated Splicing Factor as a Negative Co-regulator of the Progesterone Receptor

25 Jan 2005

Abstract excerpt

Progesterone is essential in all species for the maintenance of pregnancy, and its withdrawal is required to activate the myometrium and to initiate labor. However, unlike most other species, progesterone levels do not fall at term in humans, raising the paradox as to how labor can occur under the continued influence of progesterone. We hypothesized that an endogenous (myometrial) repressor of the progesterone...

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Share to Cytokine Signaling Pathways and Interactions
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15668243
DOI: 10.1074/jbc.m409187200

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