Article
The riboflavin kinase encoding gene ribR of Bacillus subtilis is a part of a 10 kb operon, which is negatively regulated by the yrzC gene product.
FEMS microbiology letters - 1 Feb 2005
Solovieva Irina M, Kreneva Rimma A, Errais Lopes Lubov, Perumov Daniel A
Abstract excerpt
The riboflavin kinase encoding gene ribR is situated within a 12 genes locus ytmI-ytnM of the Bacillus subtilis chromosome. Here we demonstrate that ribR is transcribed as part of a 10 kb ytmI-ytnM operon. The riboflavin overproduction phenotype of B. subtilis ribC mutant strains, which is a result of the strongly reduced flavokinase activity of the riboflavin kinase/FAD synthetase RibC, was suppressed by ribR...
Topics
- Amino Acid Sequence
- Bacillus subtilis
- Bacterial Proteins
- Base Sequence
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Operon
- Phosphotransferases (Alcohol Group Acceptor)
- Riboflavin
- Sequence Analysis, DNA