Article
[Multifunctional regulatory mutation in Bacillus subtilis flavinogenesis system].
Genetika - 1 Oct 2009
Kreneva R A, Karelov D V, Korol'kova N V, Mironov A S, Perumov D A
Abstract excerpt
Among Bacillus subtilis riboflavin-resistant mutants we identified one, which differed from other regulatory mutants by overproduction of riboflavin and simultaneous upregulation of the rib C gene encoding flavokinase/FAD-synthase. Genetic and biochemical analysis showed that the ribU1 mutation determines a trans-acting factor that simultaneously regulates activity of riboflavin and truB-ribC-rpsO operons....
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