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Article

Development of a human acute myeloid leukaemia screening panel and consequent identification of novel gene mutation in FLT3 and CCND3.

British journal of haematology - 1 Feb 2005

Smith Matthew L, Arch Rachael, Smith Lan-Lan, Bainton Nigel, Neat Michael, Taylor Claire, Bonnet Dominique, Cavenagh Jamie D, Andrew Lister T, Fitzgibbon Jude

Abstract excerpt

A study was undertaken to develop an acute myeloid leukaemia (AML) screening panel to uncover novel recurring gene mutations. Analysis was performed on six genes known to be mutated in AML (RUNX1, FLT3, KIT, CEBPA, PTPN11 and NRAS) and an additional two candidate genes (CCND3 and FES) in a panel of 175 primary human AML samples that included all French-American-British types except M3, and all cytogenetic risk...

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Source

Identifiers

PMID: 15667533
DOI: 10.1111/j.1365-2141.2004.05324.x

Genes

CCND3
FLT3
KIT
PTPN11
FES
NRAS
RUNX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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