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Article

Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling.

The Journal of biological chemistry - 1 Apr 2005

Ning Shunbin, Huye Leslie E, Pagano Joseph S

Abstract excerpt

Genes containing an interferon (IFN)-stimulated response element (ISRE) can be divided into two groups according to their inducibility by IFN and virus infection: one induced only by IFN and the other induced by both IFN and virus infection. Although it is now clear that IFN regulatory factor 7 (IRF7) is a multifunctional gene essential for induction of type I IFNs, regulation of the IRF7 promoter (IRF7p) is...

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PMID: 15664995
DOI: 10.1074/jbc.M404260200

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