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Article

Analysis of the chromosomal region 19q13.4 in two Chinese families with recurrent hydatidiform mole.

Human reproduction (Oxford, England) - 1 Feb 2006

Zhao J, Moss J, Sebire N J, Cui Q C, Seckl M J, Xiang Y, Fisher R A

Abstract excerpt

BACKGROUND: Familial recurrent hydatidiform mole is an extremely rare autosomal recessive condition in which affected individuals have a predisposition to molar pregnancies that are diploid but biparental, rather than androgenetic, in origin. A gene for this condition has been previously mapped to a 1.1 Mb region of chromosome 19q13.4. However, investigation of further families is needed to refine the location of...

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PMID: 16239310
DOI: 10.1093/humrep/dei357

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CHM

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