Article
Precision Medicine in Obesity and Type 2 Diabetes: The Relevance of Early-Life Exposures.
Clinical chemistry - 1 Jan 2018
Estampador Angela C, Franks Paul W
Abstract excerpt
BACKGROUND: Type 2 diabetes is highly prevalent and devastating. Obesity is a diabetogenic factor, driving insulin resistance and a compensatory demand for increased insulin secretion from the pancreatic β cells; a failure to address this demand results in diabetes. Accordingly, primary and secondary prevention of obesity are at the core of diabetes prevention programs. The development of obesity and declining...
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