Cryptic causation of human disease: reading between the (germ) lines.

Abstract excerpt

Most cases of complex human diseases arise sporadically. However, usually there is a significant level of familial aggregation of risk and genetic mapping has identified the responsible gene in a few mendelian cases. Although a disease can be causally genetic, intensified mapping efforts have so far been unable to identify genes that account for more than a small fraction of the familial risk, perhaps because the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biological Evolution
• Share to Epilepsy
• Share to Gene Expression Regulation