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Article

Expression and phenotype analysis of the nephrocystin-1 and nephrocystin-4 homologs in Caenorhabditis elegans.

Journal of the American Society of Nephrology : JASN - 1 Mar 2005

Wolf Matthias T F, Lee Jeeyong, Panther Franziska, Otto Edgar A, Guan Kun-Liang, Hildebrandt Friedhelm

Abstract excerpt

Nephronophthisis (NPHP), an autosomal-recessive cystic kidney disease, is the most frequent genetic cause of end-stage renal failure in children. NPHP types 1 and 4 are caused by mutations in NPHP1 and NPHP4, encoding the proteins nephrocystin-1 and nephrocystin-4, respectively. Nephrocystin-1 and nephrocystin-4 are expressed in primary cilia of renal epithelial cells. NPHP1 and NPHP4 are highly conserved in...

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Identifiers

PMID: 15659564
DOI: 10.1681/ASN.2003121025

Genes

NPHP1
NPHP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression and phenotype analysis of the nephrocystin-1 and nephrocystin-4 homologs in Caenorhabditis elegans.PMID 15659564Read ↗

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